Abstract: The large-scale relocation of chemical companies in China's large and medium-sized cities has resulted in a large number of industrially polluted sites left over around the city. The research and development of high-efficiency and low-cost remediation technologies is of great significance for realizing the green and sustainable development of industrially contaminated sites in China. Through a review of the existing physicochemical and bioremediation technologies, the importance of biotechnology in the remediation of organically contaminated sites was put forward, and the current challenges faced by the remediation of organic contaminated sites the aspects of soil environment and microorganisms were summarized. Finally, further research suggestions were offered for the bioremediation of organically contaminated sites, including the development of efficient, durable and stable inoculants and enzyme preparations, as well as the use of synergistic bioremediation additives and microbial inoculants.