Abstract: All-solid-state potentiometric sensors without internal liquid are easy to be miniaturized, arrayed and prepared into disposable paper-based electrodes and flexible plastic electrodes, thus, they have been applied in the fields of environmental monitoring, point-of-care and development of wearable devices. This paper summarized the application of nanomaterials and conductive polymers as solid contact layers for all-solid-state potentiometric sensors, sensitive membrane based on aptamers and other biomolecules in the preparation of all-solid-state potentiometric sensors in recent years, and the latest research progress of paper-based and wearable solid-state potentiometric sensors, and finally looked forward to their future development trends.