Abstract: According to the national laws and regulations about hazardous chemicals, combined with the hidden dangers investigation requirements of hazardous chemicals enterprises in a certain district, the dangerous chemicals production enterprises in a certain area were investigated and diagnosed. The results showed that the hidden dangers in the workplace, Class A and B warehouses, anti-static measures, gas cylinder management and explosion-proof area management urgently needed to be rectified. In combination with the hidden dangers investigation process and rectification, it was recommended that the hazard investigation of hazardous chemicals should be upgraded from the attention of management personnel; increase investment in safety production, strengthen law enforcement at all levels; promote the implementation of the main responsibility of enterprise safety production to jointly promote the investigation of hidden dangers ability and hidden dangers of rectification work.