Abstract: The various operating parameters of enhanced coagulation such as type and dosage of coagulants and pH on water purification effect for The Yangtze River raw water of Qingcaosha Reservoir, as current water source in Yangshupu drinking water treatment plant were investigated in this study. The Water quality parameters including degree of turbidity, UV₂₅₄, UV₂₇₂, total organic carbon (TOC) and total nitrogen (TN) were analyzed. The results illustrated that the optimal experimental conditions were as follows: the pH of the solution was 8, the polyaluminum chloride (PAC) was the best coagulant and its dosage was 4.5 mg/L, and the polyacrylamide (PAM) dosage was 0.1 mg/L, although for TOC (36.29%) and TN (5.5%) removal effect was limited, but the optimal removal rates of turbidity, UV₂₅₄ and UV₂₇₂ were 90.19%, 58.97% and 64.76%, respectively, so as to achieve the purpose of conventional purification and standard compliance. The consequences of this paper can provide theoretical and technological basis for upgrading of the process and operation optimization of original drinking water treatment plants in Yangshupu drinking water treatment plant.