Abstract: Depression is the most disabling and suicidal mental illness worldwide. Drug therapy has serious adverse reactions and dependence, and is only suitable for some patients. A growing number of researchers focus on aromatherapy, trying to explore its mechanism and analyze its effect. Aromatherapy has been gradually accepted as a supplementary medical treatment in modern medicine. Numerous clinical trials and meta-analyses have shown that aromatherapy has good effects and great potential in the treatment of depression. It has become one of the most popular clinical intervention methods for people with depression, which has guiding significance for curing diseases and developing new drugs.