Abstract: For the defect of high energy consumption in the process of 1,4-butanediol co-producing maleic anhydride and phthalic anhydride using mixed C₅ as raw materials, the energy consumption of the 1,4-butanediol production process was analyzed and optimized through the simulation and the pinch point technology, and the heat exchange network was further integrated and optimized to achieve energy-saving effects. The research results showed that 10239.3 kW of heat utility and 21683.2 kW of cold utility were saved, and equipment costs were decreased because the number of heat exchange units was reduced from 44 to 32.